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Weight loss can also lower your risk of longer-term problems linked to PCOS, including type 2 diabetes, high blood pressure and fatty liver disease
Recently, it was confirmed that GLP-1 receptor agonists consistently reduce number of atherothrombotic events and have positive effects on kidney function in patients with type 2 diabetes (30)
TRIUMPH-2: obesity with type 2 diabetes TRIUMPH-2 mirrors TRIUMPH-1 in design but enrolls adults with type 2 diabetes
Neither study showed a significant increase in amylase (7% for both studies) or lipase (28% in the LEADER trial and 31% in the SCALE trial) values after starting liraglutide compared with placebo, and the positive predictive values of amylase and lipase for pancreatitis were less than 1%
Before Retatrutide, every weight loss attempt fell apart within weeks
doi: 10.12659/MSM.920989 [DOI] [PMC free article] [PubMed] [Google Scholar] 98
