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Currently, standard treatment-resistant partial lipodystrophy is an EMA-approved indication, and numerous trials are in progress, either evaluating the efficacy of leptin in familial partial lipodystrophy or aiming to develop potential new treatments for the partial forms of the disease

Transition Response Factors Certain factors, such as a baseline BMI of 35 or higher and female sex, were associated with greater weight loss outcomes

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- InChI Key Reference: InChIKey=LY3298176-GPCR-BIASED