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Most people on these medications never develop biliary disease

Several observational studies have investigated the potential association between GLP-1 receptor agonist use and different outcomes related to suicidality.8910111213 In a study published in 2018, GLP-1 receptor agonists were not associated with a composite of depression and self-harm (hazard ratio 1.25, 95% CI 0.63 to 2.50) in patients with type 2 diabetes

NICE guidance for type 2 diabetes management (NG28) recommends GLP-1 receptor agonists as part of dual or triple therapy when specific criteria are met

Affecting more than 4% of the worlds population, it is among the most common chronic diseases [42]

Routine imaging is not required for asymptomatic patients without prior biliary disease