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Locomotor activity is an innate behavior that can be triggered by gut-motivated conditions, such as appetite and metabolic condition

Glucagon-like peptide-1 (GLP-1) is a peptide hormone secreted by the small intestine upon food intake
It revealed a higher affinity compared to the interaction of the individual GLP-1 and HSA-binding DARPin with the GLP-1 receptor and human serum albumin, respectively

Conclusion GLP1-RA therapy with liraglutide or semaglutide for 12 months is efficacious and safe for the treatment of weight regain following bariatric surgery
