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The most significant decline was noted in patients with CRP10.1mg/dl

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Metformin has been largely studied in the past years without convincing evidence of improving NAFLD

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Executive Summary Introduction

Mechanistic Insight Interestingly, only ~52% of the improvement in insulin resistance (HOMA2-IR) appears attributable to weight loss, pointing toward an additional GIP-mediated metabolic effect with tirzepatide