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Others have loftier ambitions: They hope to harness the drugs powerful effects to achieve better health and longer lives without losing a lot of weight or experiencing side effects such as GI issues and muscle loss

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However, excessive cardio can increase appetite and accelerate muscle loss if nutrition does not compensate

The use of sodium-glucose co-transporter-2 inhibitors or glucagon-like peptide-1 receptor agonists versus sulfonylureas and the risk of lower limb amputations: A nation-wide cohort study

With obesity rates rising, the public health challenge is significant