sglt2 vs glp 1 GLP-1 receptor agonists and inhibitors: a couple at last? Blood pressure effects of SGLT2

In short, the standard prescribe and refer back in 3 months approach leaves a support vacuum

For the tablet, people taking the maximum dose of 25mg once a day lost an average 17% of their weight after 64 weeks

Common side effects of Ozempic usage include feelings of nausea, vomiting, diarrhea, and discomfort in the abdomen

It also increases energy expenditure, possibly due to increased activity in the sympathetic nervous system and changes in fat metabolism Semaglutide GLP-1 improved insulin sensitivity, increased energy expenditure, fat oxidation, and reduced inflammation can result in significant weight loss and sustained weight management with Semaglutide GLP-1 therapy

Between these two, metformin is our first-line preference as it helps not only with antipsychotic-related weight gain but also with the metabolic side effects of antipsychotics (insulin resistance, fasting glucose, triglycerides, and hyperprolactinemia), earning it a recommendation from the APA for this purpose

It is your responsibility to review information provided by your pharmacy and consult with your doctor or health care team member prescribing these medications with any questions about your medication.