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MASLD is also often accompanied by an altered microbial metabolite profile, characterized by reduced short-chain fatty acids (SCFAs) and increased trimethylamine N-oxide (TMAO) (Naghipour et al., 2021)

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And in August, Pfizer ended development of its third and final oral GLP-1 candidate, PF-06954522, after a review of its phase 1 clinical performance and the overall GLP-1 landscape