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Evidence-based UK guidance.

Semaglutide offers proven weight loss and cardiovascular protection, but not everyone needs it

#Obesity #GLP1 #Tirzepatide #Semaglutide #WeightManagement #ObesityMedicine #MetabolicHealth #ChronicDisease #Endocrinology #DiabetesCare

Switching to the oral small molecule glucagon-like peptide-1 (GLP-1) orforglipron after taking injectable GLP-1s helped patients maintain mostbut not allof their weight loss, according to a clinical trial led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

LVEF, left ventricular ejection fraction