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A., Do, H

In the face of ongoing shortages of the obesity and diabetes medications known as GLP-1s, patients have resorted to a wide array of sources for the drugs, including medical spas and telehealth sites that prescribe compounded versions of the drugs

Meanwhile, the cardiovascular diseases sub-segment emphasizes the cardioprotective effects of GLP-1 receptor agonists

Benefits include appetite suppression, fat burning, reducing cravings, stabilizing blood sugar, supporting weight management, and boosting heart health

Importantly, localized increases in GLP-1, such as that occur in the gut and portal vein, often have a more profound effect than systemic elevations, emphasizing the therapeutic potential of targeting regional activity rather than relying solely on systemic concentrations

J Lipid Res 2014;55:681-97.ArticlePubMedPMC 74
