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PLoS Comput Biol (2012) 8(9):e1002687

The FDA reportedly contacted the manufacturer suggesting that the drug had not been marketed in a truthful and non-misleading way

5 Given these effects, GLP-1RAs have become a cornerstone in the treatment of metabolic disorders, especially in patients who not only need glycemic control but also weight reduction to improve their overall health outcomes

These drugs have tremendous benefit, but more ongoing studies are needed outside of patients with diabetes, obesity, and metabolic disease before we can apply safely, says Srinath
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A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver

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