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As insurance coverage expands and out-of-pocket costs fall, use of GLP-1 drugs is likely to increase further, especially for weight loss

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The sustained activation of GLP-1 receptors leads to increased insulin synthesis, beta cell proliferation and their resistance to apoptosis, and improved survival [9]

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Ozempic is approved to manage blood glucose levels and A1C in people with type 2 diabetes and Wegovy or weight loss in people with certain BMIs and health conditions

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But no clinical trial has tested it

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Beginners should start at 250 mcg daily to assess individual tolerance and response before potentially increasing the dose

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Anaerobe 14(1):4348

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