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As insurance coverage expands and out-of-pocket costs fall, use of GLP-1 drugs is likely to increase further, especially for weight loss

The sustained activation of GLP-1 receptors leads to increased insulin synthesis, beta cell proliferation and their resistance to apoptosis, and improved survival [9]

Ozempic is approved to manage blood glucose levels and A1C in people with type 2 diabetes and Wegovy or weight loss in people with certain BMIs and health conditions

But no clinical trial has tested it

Beginners should start at 250 mcg daily to assess individual tolerance and response before potentially increasing the dose

Anaerobe 14(1):4348
