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Off-label antiobesity treatment in patients without diabetes with GLP-1 agonists in clinical practice

10.3390/nu17081303 [DOI] [PMC free article] [PubMed] [Google Scholar] Granata A, Maccarrone R, Anzaldi M, Leonardi G, Pesce F, Amico F, et al (2022) GLP-1 receptor agonists and renal outcomes in patients with diabetes mellitus type 2 and diabetic kidney disease: State of the art

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The glucagon receptor agonism is thought to play an important role in hepatic fat reduction: preclinical and early clinical data suggest that glucagon stimulates hepatic fatty acid oxidation and promotes lipid export from the liver, potentially reducing intrahepatic triglyceride content

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