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Description

It remains to be seen how avidly the agency will pursue 503As that are still filling telehealth and medspa orders

Abstract Importance: GLP-1 receptor agonists (GLP-1 RAs) are widely recognized for their antidiabetic properties, primarily due to their insulin secretagogue action

doi: 10.1067/S0022-3476(03)00386-X 16 MuscogiuriGBarreaLFaggianoFMaiorinoMIParrilloMPuglieseGet al

preclinical and clinical evidence

Given TRPM2s role in both atherosclerosis and GLP-1-induced insulin secretion as discussed above [21], further research on GLP-1/TRPM2 interactions could enable further pharmacological targeting of macrophage-related inflammation in diabetes and ASCVD