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In contrast, PWA mice display overt metabolic perturbations, including overweight and impaired glucose homeostasis 46 , and may mimic the canonical human phenotype A of PCOS linked to hyperandrogenism, anovulatory cycles, and polycystic ovarian morphology 45

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Other medications may target hormonal pathways or metabolic processes to promote weight loss
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Treating reproductive-aged women with GLP-1 receptor agonists: cardiometabolic opportunity and reproductive considerations

But low levels of estrogen are a well-known cause of night sweats