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State-Level Changes: Some states may consider pilot programs to study the long-term cost-effectiveness of covering these drugs

Louis EK, Rieck TM, Haider CR, Holmes DR et al

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GLP-1 agonists are typically initiated at low doses and gradually increased according to manufacturer guidelines, which helps minimise gastrointestinal side effects and may moderate the pace of weight reduction
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The precedent it set on Makena, and potentially now tirzepatide, could leave the agency hard-pressed to maintain control over these critical policies in the future
