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Outcome 2: Delayed drinking There are also lab experiments

Adding phentermine, which can also cause gastrointestinal disturbance and dry mouth, may compound these symptoms and reduce treatment tolerability

For addiction, the cleanest open test is a properly powered, treatment-seeking trial in cocaine or methamphetamine use disorder, a design that carries no weight-loss confound and measures a behavior close to the proposed mechanism

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A1C and fasting glucose

Growing clinical evidence supporting significant weight reduction and cardiovascular protection is accelerating physician adoption