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However, a growing number of patients encounter a final hurdle: loose, hanging skin

Berberine is not a GLP-1 agonist, though both compounds influence metabolic pathways

Combining GLP-1 medications like semaglutide with antidepressants such as bupropion requires medical oversight

This newly charted pathway - separate from previously described mechanisms that broadly affect appetite - could be an avenue by which GLP-1s treat other dysfunctions in reward processing, such as substance use disorder

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