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Control of satiety also occurs when GLP-1R + neurons in the nucleus tractus solitarius of the hindbrain are stimulated, and this occurs independently of aversion caused by activation of GLP-1R + neurons in the area postrema [36]

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doi: 10.1210/en.2017-00564

Research since 2023 has shown improvements in ovulation and menstrual regularity for some patients using GLP-1s (Escobar-Morreale et al., 2024)
Underlining the role of PCSK2 in liberation of glucagon via proglucagon processing, PCSK2-deficient mice are slightly hypoglycemic upon fasting, have a reduced rise in blood glucose following intraperitoneal glucose administration, display impaired processing of Gcg in the -cells, and develop -cell hyperplasia [154,155]
