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Genomic evidence of GLP-1 receptor as target for the treatment of substance use disorders
doi: 10.3389/fphar.2015.00264
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Cardiovascular events tended to be reduced with tirzepatide, meeting the criteria for cardiovascular safety
Despite this potential, given the known long-term benefit of lowering hemoglobin A1c in preventing DR progression, there does not appear to be any contraindication to initiating GLP-1/GIP agonist therapy with appropriate ocular monitoring
