glp-1 weight loss explained Tirzepatide Explained: The Future of Management Indications for GLP-1/GIP RA Summary

Steinert RE, Feinle-Bisset C, Asarian L, Horowitz M, Beglinger C, Geary N

Lets not all just jump on the bandwagon

The only other meta-analysis that examined the effect of GLP-1 RAs on clinical parameters was Ye et al

Dosing considerations GLP-1 dosing follows standard titration protocols regardless of HRT status

For patients using Mounjaro, Ozempic, or other GLP-1 medications for blood sugar management, stopping usually leads to worsening glycemic control within weeks

Accordingly, claims of long-term structural renoprotection should be interpreted cautiously until kidney-focused trials and longer follow-up data confirm benefits on hard renal endpoints (eGFR slope, ESKD)