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That record is easier to discuss than scattered screenshots, and it keeps the calculator in its proper role: a tool for organizing information, not a tool for making medical decisions

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Thiazolidinediones (such as pioglitazone) improve insulin sensitivity but are used less frequently due to side effect profiles

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With expanded coverage, the researchers predicted that incremental Medicare drug costs would total nearly $66 billion over 10 years, with only $18 billion saved through reduced hospitalizations and chronic disease care, leading to a net total of $48 billion in new spending

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Sanofi's latent estate, Hanmi's clinical fortress, Indiana University's foundational scaffold, the Chinese asset-by-asset build, and the combination-centric bets AstraZeneca and Novo are assembling all map to the decade-plus value-capture window that sits behind the approval milestones

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