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Just because something doesnt work for you now, that doesnt mean there wont be something to help you in the future. If you have questions about weight loss, talk to your doctor

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Without titration, the sudden introduction of 8 mg or 12 mg would likely have produced far more intolerances and early withdrawals, compromising the validity of the results

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These results were not stratified according to BMI, as this could also lead to fewer exacerbations and the possible impact due to weight loss was not considered