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A greater reduction in body weight, cholesterol, triglycerides, fasting glucose, insulin, and HOMA-IR was achieved with the higher dose of tirzepatide, demonstrating a clear dose-dependent improvement

Sammarco, G
Diabetes and PGC-1 are closely linked

Some patients reach their goal weight loss and stop titrating rather than advancing to maximum dose
Heather Ferris: They are part of a class of drugs called GLP-1 receptor agonists

Do not start, stop, or modify any medication without working with a prescriber