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Abnormalities in the genioglossus muscle and its neuromuscular synapse in leptin-deficient male mice

Add-on to metformin SURPASS-2 (NCT03987919) was a 40-week open-label trial (double-blind with respect to MOUNJARO dose assignment) that randomized 1879 adult patients with type 2 diabetes mellitus with inadequate glycemic control on stable doses of metformin alone to the addition of subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, or MOUNJARO 15 mg once weekly or subcutaneous semaglutide 1 mg once weekly

Key indicators of potential overdose include severe gastrointestinal distress, unexplained dizziness, or sudden swelling

According to research, data from trials like STEP 1 and SUSTAIN 8 indicates that approximately 40% of the weight lost by patients taking semaglutide can be attributed to lean mass, primarily muscle tissue, raising concerns about potential cardiovascular and bone health risks due to muscle loss

I have been losing weight weekly and the price is doable for me

(2) high-fat and high-carbohydrate (Food HiF/HiC )