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Additionally, through microbial modulation, FMT appears to improve intestinal barrier functioning and reducing intestinal permeability, providing an important contribution in NAFLD/NASH management by decreasing hepatic fat accumulation and inflammation, both in humans and mice [80]

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Activation of GLP-1R also triggers the PI3K/Akt signaling pathway via the subunits of G proteins, thereby promoting -cell viability and replicative capacity (Kaihara et al., 2013)

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