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Patients taking GLP-1 receptor agonists in combination with insulin or sulfonylureas face increased hypoglycemia risk and should be counseled to check blood glucose when experiencing these symptoms

Serious hypersensitivity reactions including anaphylaxis and angioedema have been reported with semaglutide tablets [see Warnings and Precautions (5.7)]

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Conrad N., Misra S., Verbakel J

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Humalog is contraindicated in people with hypersensitivity to insulin lispro or any other ingredients contained in the drug