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Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimers disease

[DOI] [PubMed] [Google Scholar] 36

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On the day of the experiment, the culture medium was replaced with DMEM containing 5.6 mM glucose and 0.1% bovine serum albumin (BSA) and the cells were then serum starved for 3 hours while equilibrated in a tissue culture incubator

Originally approved for type 2 diabetes, the diabetes drug Mounjaro not only treats diabetes but also aids in weight control, leading to its off-label use for obesity

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