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The REALIZE-K trial evaluated the efficacy of sodium zirconium cyclosilicate (SZC) in enabling the optimization of mineralocorticoid receptor antagonist (MRA) therapy, specifically spironolactone, in patients with heart failure with reduced ejection fraction (HFrEF) who had hyperkalemia or were at high risk for it

While not everyone will experience constipation, those who do may face an increased risk of hemorrhoids due to straining and prolonged sitting during bowel movements

PlexusDx offers the Precision Peptide Genetic Test ($99 add-on after first month of treatment), which maps your genetic response across 14 appetite-regulation pathways and 150+ insights related to how your body responds to GLP-1 therapy

Pratley and Gilbert 2008

More frequent and lower dose SubQ testosterone injections have been proven to keep your levels more stable without having you go through the yo-yo or up and down effects

In trials, some participants achieved complete resolution of liver fat accumulation, while others experienced substantial improvements in liver enzyme levels and fat content