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Endocrinology 156, 255267

Conflicts of Interest The authors have no conflicts of interest to declare

Effects on caloric intake and body weight Decreased calorie intake due to increased satiety and decreased appetite Decreased body weight , with more fat loss than lean mass loss) 2

The argument that wins: Request a formulary exception

Sudden kidney failure or worsening of existing kidney conditions

8.3 Clinical decision matrix: stratification by metabolic phenotype and reproductive timeline 8.3.1 Dimensions Vertical Axis: High Risk: BMI 30 kg/m 2 comorbid with IR, MASLD, impaired glucose tolerance (IGT), or a significant family history of cardiovascular disease