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(c) Are v forgetting the exceptionally LONG LIST of AE's of Sema & other GLP1a

For current practice, the most defensible use of GLP-1RAs is as a time-bounded metabolic optimization strategy in women with meaningful obesity/insulin-resistance burden, with reproductive endpoints interpreted as potential downstream gains rather than guaranteed direct effects (111, 112, 124)

If you take other diabetes medications, particularly insulin or sulfonylureas, there is an increased risk of hypoglycaemia

The app's protein-focused home screen is tailored to help mitigate muscle loss risks tied to GLP-1 therapy

[DOI] [PubMed] [Google Scholar] Wettergren A, Wjdemann M, Meisner S, Stadil F, Holst JJ

Nevertheless, as demonstrated in the STENO-2 trial, residual renal and risk and overall mortality remains high, also due to the fact that the different treatment targets are often not reached [4]
