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26 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al

10.1111/jdi.12956 127 YingX.RongjiongZ.KahaerM.ChunhuiJ.WulasihanM

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The direct cardiovascular effects represent a combination of platelet inhibition, augmented fibrinolytic responses, and attenuated thrombogenesis that collectively address not only the prothrombotic phenotypes of DM mellitus, obesity, and chronic kidney disease but a novel prevention approach beyond traditional risk factors for myocardial infarction, ischemic stroke, and cardiovascular death [90, 91]