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In clinical trials, retatrutide at the 12mg dose produced greater average weight loss (24.2-28.7%) than tirzepatide at 15mg (~18%)
For reconstitution math, the peptide reconstitution calculator takes the guesswork out of dilution

Lotte S, Sofie P, Cathrine O, et al

Diabetes Obes Metab 26: 54745478
The detailed methods for model construction and evaluation are provided in Supplementary Methods 1
