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Forslund K, Hildebrand F, Nielsen T et al (2015) Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

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However, when progesterone signaling is deficient or functionally resisted, as reported in both PCOS and endometriosis, the resolution phase is disrupted, resulting in persistent cytokine production, prolonged leukocyte activation, and impaired endometrial homeostasis (Salamonsen and Woolley, 1999)

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