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Description
Our findings demonstrated that both natural and synthetic GLP-1 administration altered heat sensitivity and that local administration of GLP-1 notably reduced heat sensitivity and CAP-induced spontaneous pain behavior

Whilst our naturally produced GLP-1 only lasts for a few minutes after release, these medication are said to stick around for up to 14 hours

Further translational research and prospective clinical trials are required to clarify causality, determine effect size, and identify high-risk groups most likely to benefit

Serious adverse events are rare with properly supervised GLP-1 therapy
Given the near-total absence of safety data on these drugs during pregnancy, every prescribing specialist applies the same rule: discontinue at least two months before attempting conception or embryo transfer

Huang et al
