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Therefore, it can be concluded that GLP-1 inhibits bone resorption in a calcitonin-dependent way ( However, the results from preclinical studies have not necessarily extended to success in clinical studies

With TRIUMPH-4 (December 2025, 28.7% weight loss), TRIUMPH-1 (May 2026, 28.3% in 2,339 patients), and now TRANSCEND-T2D-1 (June 2026, the first diabetes-specific Phase 3 readout) all confirmed, this investigational medication is rapidly approaching regulatory review

The American Society of Anesthesiologists has issued guidance on this topic, and individual surgical practices continue to refine their protocols as more data becomes available

p -value 0.5073]) and liraglutide (RR 4.5063 [95% CI 0.2428, 83.6327