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Semaglutide, a GLP-1 receptor agonist approved in 2021, demonstrated much greater weight loss than previous medications, which stimulated the development of poly-agonists that combine GLP-1 receptor agonism with GIP and glucagon receptor agonism

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As of January, 13 state Medicaid programs cover GLP-1s for obesity treatment

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We counted the number of unique products on each companys 2025 list

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