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Current therapies often show limited long-term efficacy, side effects, or require frequent administration, underscoring the need for safer, longer-acting interventions 24

These conditions may affect spermatogenesis through overlapping endocrine, inflammatory, oxidative and epigenetic mechanisms, as well as through effects on sexual function and overall cardiometabolic health (Figure 2)

Essentially, this is an opportunity to make our whole population healthier, not only through the drugs themselves, but through the cultural shift to focus on nutrition, exercise, lifestyle, our environment, the way that we deliver food in this country, it really presents itself with an opportunity to improve the overall health of our population
Obesity as a disease: no lightweight matter

Because of this, some doctors are recommending that older adults, especially those over 65, consider GLP-1 drugs like Ozempic to manage their weight but also to improve their overall health and longevity
Other common side effects of GLP-1 agonists: diarrhea or constipation abdominal pain belching, gas, or heartburn feeling bloated injection site reactions vomiting Your clinician will offer you tips for managing side effects , as well as share common contraindications (reasons to not take semaglutide), including a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia
