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Moreover, all included studies were RCTs

Analysis of specific topic This literature review was conducted following the PICO Framework, with details available in Supplementary material 1

But doctors say comparing the two is like comparing apples and oranges

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[DOI] [PubMed] [Google Scholar] 69.Abbott CR, Monteiro M, Small CJ, et al

Standard four-week titration blocks The Phase 2 trial protocol followed a consistent pattern
