is contrave a glp-1 drug - New Obesity Medication Now Available Contrave - W8MD's NYC GLP-1

(Left) In liver cells, GLP-1 can mediate cholesterol efflux by acting directly on LXR, or by inducing an increase in ATP-binding cassette transporter A1 (ABCA1) mRNA through Ca2+/calmodulin (CaM)-dependent protein kinase kinase/CAM-dependent protein kinase IV/Prolactin regulatory element binding (CaMKK/CaMKIV/PREB), increasing apolipoprotein AI (apo AI) mRNA and promoter expression, and increasing apo AI secretion, thereby mediating intracellular cholesterol efflux

A woman from Louisiana claims she was prescribed the drugs by her doctor and experienced severe gastrointestinal side effects, including gastroparesis

PLoS One 8 , e78154, (2013)

Metformin is available as a tablet, liquid, or extended-release (ER) formulation, and the dosage strengths and frequency vary depending on the form

Diabetes Care 2016;39: 701-8

When the body loses weight on these medications, it loses both fat and lean muscle mass