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[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Rao Y, Lu M, Ge F, Marsh DJ, Qian S, Wang AH, et al

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It functions as a dual GIP/GLP-1 receptor agonist, meaning one peptide chain binds to and activates both the glucose-dependent insulinotropic polypeptide receptor and the GLP-1 receptor

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One strategy some research users report is maintaining a lower maintenance dose rather than stopping entirely, similar to how the clinical trial community is now discussing long-term low-dose maintenance for GLP-1 class medications broadly

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