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In addition, a catalytically active soluble form of DPP4 is also present in plasma

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Diabetes Obes Metab 2022
The researchers identified PEN2 as a metformin binding partner that forms a complex with ATP6AP1, leading to AMPK activation through inhibition of the lysosomal v-ATPase

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Presented at: 66th Scientific Sessions of the American Diabetes Association
