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The accumulation ratio (the factor by which steady-state levels exceed single-dose levels) equals 1/(1 - e^(-0.693 * dosing_interval / t_half))
Exposure to phentermine or GLP-1 medications in the first trimester yielded similar results to exposure in the 90 days prior to pregnancy, as shown in Figure 3

Gen Comp Endocrinol (2018) 260:517

A double-blind, controlled trial

These are all carbohydrate-dominant foods