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Genetics of Prader-Willi Syndrome Three distinct genetic mechanisms are responsible for PWS: approximately 65% to 70% of cases result from paternal deletion of 15q11.213, 20% to 30% are caused by maternal uniparental disomy of chromosome 15, and the remaining 2% to 5% of cases result from imprinting center defects or chromosome 15 rearrangement [1519]

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They may also investigate underlying causes of pain and optimise your diabetes management to minimise Rybelsus-related side effects

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It also helps doctors decide if more treatment cycles are needed or if it is time to consider alternative treatment options [4, 5]