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Patients with lipedema should undergo thorough medical evaluation before starting therapy

As is reflective of the wider under-recognition of women in science, women's contributions to the development of GLP-1 drugs have taken time to be fully appreciated (Barany, Barany)

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This indicates that their cardiometabolic benefits are primarily mediated by weight loss, IR alleviation, and improvements in triglyceride-rich lipoprotein pathways, rather than a direct reduction in LDL-C levels