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Across the SLD spectrum, GLP-1 RAs demonstrated modest but directionally consistent improvements in liver enzyme profiles (alanine aminotransferase [ALT] and aspartate aminotransferase [AST]), with 4 of the 7 ALT outcome estimates showing significant reductions, and 4 of the 9 AST outcome estimates showing significant reductions

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Thus, treatment to improve glycaemic control, using insulin (46) or a DPP-4 inhibitor (47) led to improved insulin responses to exogenous GIP

The plan appears to be a whole-foods, healthy-eating plan that prioritizes fruits, vegetables, lean protein, nuts, and whole grains over refined grains, says Samantha Cassetty, RD, of New York City

Research has shown that semaglutide can lead to long-term weight loss in people with obesity

According to the National Library of Medicine (NLM), these injectable treatments mimic the action of the naturally occurring hormone GLP-1, which helps regulate appetite and insulin secretion