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The Science Behind Weekly Dosing Retatrutide has a long half-life (around 6 days)

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This is primarily due to its remarkable ability to regulate appetite and improve metabolism

Sex differences in the efficacy of Glucagon-like peptide-1 receptor agonists for weight reduction: a systematic review and meta-analysis

doi: 10.1038/oby.2008.56

The pharmacokinetic profile of tirzepatide supports once-weekly dosing, with a half-life of approximately five days, meaning the medication remains active in your body for an extended period