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For how long can I use Mounjaro

The standard progression, starting at 2.5 mg and increasing by 2.5 mg increments every 4 weeks, emerged from extensive clinical trials designed specifically to balance efficacy against tolerability

Lobectomy resulted in a higher risk of recurrence ( P = .04) and death ( P = .04)

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Clinical trials stopped at 2mg because that dose provided the optimal therapeutic effect without causing intolerable safety risks

ESSENCE data suggest that Wegovys impact on histologic endpointsresolution of steatohepatitis without fibrosis worsening and 1stage fibrosis improvement without MASH worseningmay be mediated through these pathways and possibly direct GLP1 receptorrelated effects, although the exact mechanistic contribution beyond weight loss remains an area of active research