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Based on this review, evidence from head-to-head and insulin-comparator trials demonstrates that dual GIP/GLP-1 co-agonism consistently overcomes metabolic plateaus that result from single-pathway therapy, producing superior glycated hemoglobin reduction, bariatric-level weight loss (up to 25.3%), and robust macrovascular and heart failure protection, including a 38% reduction in composite cardiovascular risk among patients with heart failure with preserved ejection fraction (HFpEF)

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Learn how to start and convert your appropriate type 1 diabetes and type 2 diabetes patients over 1 year of age to once-daily Tresiba (insulin degludec)

Two major ongoing trials are likely to change that, with potentially big implications for clinical practice.

Under the guidance of Dr
