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Among these, GLORY-1, DREAMS-1, and DREAMS-2 have already met their primary endpoints and the other four studies are currently ongoing

Phase 3 readouts are landing on a rolling basis, but FDA approval has not happened as of June 2026

For instance, the survival rate of patients with high GNG7 expression is significantly higher than that of patients with low GNG7 expression in esophageal cancer, and low GNG7 expression leads to a deeper invasion in vitro and in vivo (Xu et al., 2019a), implying a protective role of GNG7

GLP-1 medications require evaluation by a licensed healthcare professional and may not be appropriate for everyone

Figure 1: Percentage risk reduction with GLP-1 therapy across indications based on selected real-world studies: Sources: 1